There is no effect on the brain whatsoever, these are myths circulated by ignorant people all around the world. Brain is lying much deeper inside the skull. Above the brain there are 3 layers i.e. Dura mater, Arachnoid mater and Pia mater. So, all these 3 layers along with the skull protect the brain. So, the brain is very far from the part where transplant is done. Hair Transplant procedure is done in the superficial layers of the scalp.